This product is used to qualitatively detect the content of Follicle Stimulating Hormone (FSH) in human urine, and is mainly used in the clinical diagnosis of ovarian diseases.

Strip

Card

Pen

Product Description

[Sample]

Urine

[Intended use]

This product is used for the qualitative detection of follicle-stimulating hormone (FSH) in human urinein vitro It is mainly used for auxiliary diagnosis of ovarian diseases clinically. Follicle-stimulating hormone (FSH) is a glycoprotein gonadotropin synthesized and secreted by basophils of the anterior pituitary gland, which can enter blood and urine through blood circulation. For women, FSH can promote the development and maturation of follicles, promote the proliferation of granulosa cells, cause the secretion of follicular fluid, and cooperate with LH to regulate and promote the secretion of estrogen and ovulation of mature follicles, and participate in the formation of normal menstruation. During the menstrual cycle of women, FSH undergoes cyclical changes, peaking at mid-menstrual period (before ovulation), and declining to the baseline level after ovulation. Female menopause generally occurs between the ages of 49-54 and lasts an average of 4-5 years. During this period, due to ovarian atrophy, follicular atresia and degeneration, the secretion of estrogen is significantly reduced, which stimulates the pituitary gland to secrete a large amount of gonadotropins, especially the level of FSH will increase significantly and maintain this level for a long time. Therefore, the dynamic change process of FSH in the human body can be detected at any time, so as to assist in judging whether the female ovarian function is intact, whether there is a tendency to amenorrhea, whether to enter menopause, whether children have a tendency to precocious puberty, etc.

At present, the commonly used detection methods of follicle-stimulating hormone (FSH) in clinic or laboratory include chemiluminescence method and immunochromatography method, etc.

[Testing principle]

The product adopts the principle of double antibody sandwich. When there is follicle-stimulating hormone in the sample during detection, the FSH antigen in the sample reacts with the colloidal gold-labeled mouse follicle-stimulating hormone antibody (FSH mAb1) on the binding pad to form a labeled antibody-antigen complex. The complex is chromatographed upward by capillary action and captured by a detection line (T line) mouse-derived follicle-stimulating hormone antibody (FSH mAb2)coated on a nitrocellulose membrane, and a purple/red band appears. The complex continues to be chromatographically upward and is captured by the quality control line (C line) antibody (goatanti-mouse IgG polyclonal antibody) coated on the nitrocellulose membrane, and a purple/red band appears. When the concentration of FSH in the sample is lower than the detection limit, the color of the detection line (T line) is lighter than that of the quality control line (C line). When the concentration of FSH in the sample is equal to or higher than the detection limit, the color development of the detection line (T line) is equal to or deeper than that of the quality control line (C line). Regardless of whether the sample to be tested contains FSH, the quality control line (C line) will form a purple/red color band visible to the naked eye, which is the standard for judging whether the sample volume is sufficient and whether the chromatographic process is normal, also serves as the internal control of this reagent.

Key Advantages

• High Accuracy.
• Easy to Use.
• Fast Detection: Result in 5 minutes.
• No equipment needed.
• Multiple Packaging Specifications: 1 Test/Box or 25 Tests/Box or 50 Tests/Box.

Operation Flow & Result Interpretation

Positive: Purple/red bands appear on both the test area (T) and the control area (C), and the color of thetest area (T) is equal to or deeper than the control area (C), the result is positive.

Negative: The color of the test area (T) is lighter than that of the control area (C), or there is no purple/redband on the test area (T), but purple/red bands appear on the control area (C), the result is negative.

Invalid: There is no purple/red band in the control area (C), no matter whether there is a red band in the detection area (T), the test strip/card/pen is judged to be invalid, and retesting is recommended.